US 12,129,286 B2
Membrane-bound IL-12 for cellular immunotherapy
Saul J. Priceman, Valley Village, CA (US); John P. Murad, Diamond Bar, CA (US); and Eric Lee, Diamond Bar, CA (US)
Assigned to City of Hope, Duarte, CA (US)
Filed by CITY OF HOPE, Duarte, CA (US)
Filed on Mar. 21, 2024, as Appl. No. 18/612,579.
Application 18/612,579 is a continuation of application No. PCT/US2023/064180, filed on Mar. 10, 2023.
Claims priority of provisional application 63/423,479, filed on Nov. 7, 2022.
Claims priority of provisional application 63/318,753, filed on Mar. 10, 2022.
Prior Publication US 2024/0254183 A1, Aug. 1, 2024
Int. Cl. C12N 15/24 (2006.01); C07K 14/54 (2006.01); C12N 5/0783 (2010.01)
CPC C07K 14/5434 (2013.01) [C12N 5/0636 (2013.01); C07K 2319/02 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A nucleic acid molecule comprising a nucleotide sequence encoding a polypeptide comprising the amino acid sequence of SEQ ID NO: 6 or SEQ ID NO:7.