US 12,128,396 B2
Manually-operated mono-channel or multi-channel pipettes and control button intended for such pipettes
Nicolas Paris, Nancy (FR); Frédéric Sanquer, Tremblay-en-france (FR); and Frédéric De Maack, Paris (FR)
Assigned to GILSON SAS, Villiers-le-Bel (FR)
Filed by GILSON SAS, Villiers-le-Bel (FR)
Filed on Nov. 1, 2021, as Appl. No. 17/453,107.
Application 17/453,107 is a continuation of application No. 16/339,448, granted, now 11,192,099, previously published as PCT/FR2017/052754, filed on Oct. 9, 2017.
Claims priority of application No. 16 59760 (FR), filed on Oct. 10, 2016.
Prior Publication US 2022/0048022 A1, Feb. 17, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. B01L 3/02 (2006.01); G01N 35/00 (2006.01); G01N 35/10 (2006.01)
CPC B01L 3/0237 (2013.01) [G01N 35/00871 (2013.01); G01N 35/1009 (2013.01); B01L 2200/0605 (2013.01); B01L 2200/146 (2013.01); B01L 2300/023 (2013.01)] 19 Claims
OG exemplary drawing
 
1. An actuating knob for equipping a manually-operated pipette for sampling and dispensing a sample of a liquid according to a user-selected predefined protocol, the actuating knob comprising:
an autonomous control device that comprises:
a microcontroller,
a wireless communication module enabling said actuating knob to communicate with a first set of sensors for measuring physical quantities related to the pipette and a second set of sensors for providing data relating to an environment of a pipetting operation to the autonomous control device, and communicate with an information processing apparatus adapted to compare the measured physical quantities related to the pipette and the data relating to the environment of the pipetting operation with expected data of the user-selected predefined protocol, wherein a fault is determined if a value corresponding to the measured physical quantities and the data relating to the environment of the pipetting operation is outside of a range of predetermined validity limits, the predetermined validity limits corresponding to the expected data, and when the fault is detected, an error signal associated with the fault is transmitted to the autonomous control device, and
an alarm module adapted to generate, upon reception of the error signal, an alert signal that is transmitted, in real time, to a user
wherein the actuating knob is configured to communicate with other connected pipettes and/or with automated pipetting systems, and/or with connected sensors relating to the user-selected predefined pipetting protocol.