	US 12,128,075 B2
	Compositions and methods comprising bacteria for improving behavior in neurodevelopmental disorders
Elaine Hsiao, Rowland Heights, CA (US); Sara McBride, Pasadena, CA (US); Sarkis K. Mazmanian, Porter Ranch, CA (US); and Paul H. Patterson, Altadena, CA (US)
Assigned to California Institute of Technology, Pasadena, CA (US)
Filed by California Institute of Technology, Pasadena, CA (US)
Filed on Jun. 10, 2021, as Appl. No. 17/303,946.
Application 17/303,946 is a division of application No. 16/139,741, filed on Sep. 24, 2018, abandoned.
Application 16/139,741 is a continuation of application No. 14/925,242, filed on Oct. 28, 2015, granted, now 10,124,025, issued on Nov. 13, 2018.
Claims priority of provisional application 62/072,873, filed on Oct. 30, 2014.
Prior Publication US 2022/0016185 A1, Jan. 20, 2022
Int. Cl. A61K 35/744 (2015.01); A61K 35/74 (2015.01); A61K 35/00 (2006.01)

CPC A61K 35/744 (2013.01) [A61K 35/74 (2013.01); A61K 2035/115 (2013.01); Y02A 50/30 (2018.01)]

6 Claims

1. A composition for improving a sensorimotor gating performance in a subject, the composition consisting of:

a mixture of Enterococcus faecalis and Bacteroides fragilis;

a mixture of E. faecalis, Bacteroides fragilis, and Bacteroides thetaiotaomicron;

a mixture of E. faecalis, Bacteroides fragilis, and Bacteroides vulgatus;

a mixture of E. faecalis, Bacteroides fragilis, Bacteroides thetaiotaomicron, and Bacteroides vulgatus;

and

polyethylene glycol (PEG),

wherein the composition is formulated as a probiotic composition for oral administration.