US 12,127,943 B2
Cartilage mosaic compositions and methods
Carolyn Barrett Rorick, Denver, CO (US); and Yaling Shi, Larkspur, CO (US)
Assigned to AlloSource, Centennial, CO (US)
Filed by AlloSource, Centennial, CO (US)
Filed on Jul. 29, 2021, as Appl. No. 17/388,388.
Application 17/388,388 is a continuation of application No. 16/459,136, filed on Jul. 1, 2019, granted, now 11,123,193.
Application 16/459,136 is a continuation of application No. 15/608,679, filed on May 30, 2017, granted, now 10,335,281, issued on Jul. 2, 2019.
Application 15/608,679 is a continuation of application No. 14/875,258, filed on Oct. 5, 2015, granted, now 9,700,415, issued on Jul. 11, 2017.
Application 14/875,258 is a continuation of application No. 14/187,093, filed on Feb. 21, 2014, granted, now 9,186,253, issued on Nov. 17, 2015.
Claims priority of provisional application 61/768,190, filed on Feb. 22, 2013.
Prior Publication US 2021/0353422 A1, Nov. 18, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 2/30 (2006.01); A61L 27/36 (2006.01)
CPC A61F 2/30756 (2013.01) [A61L 27/3608 (2013.01); A61L 27/3612 (2013.01); A61F 2002/30113 (2013.01); A61F 2002/30153 (2013.01); A61F 2002/30154 (2013.01); A61F 2002/30759 (2013.01); A61F 2002/30784 (2013.01); A61F 2002/3097 (2013.01); A61F 2240/002 (2013.01); A61F 2310/00359 (2013.01); A61F 2310/00371 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A mosaic cartilage composition comprising:
a cartilage sheet comprising a plurality of interconnected cartilage tiles that are separated by channels formed in the cartilage sheet, wherein the cartilage sheet comprises seeded viable mesenchymal stem cells; and
a biocompatible carrier.