US 12,127,876 B2
Functional transcranial doppler ultrasound and methods of use
Sandra A. Billinger, Roeland Park, KS (US); and Eric D. Vidoni, Roeland Park, KS (US)
Assigned to University of Kansas, Lawrence, KS (US)
Appl. No. 17/284,758
Filed by University of Kansas, Lawrence, KS (US)
PCT Filed Oct. 11, 2019, PCT No. PCT/US2019/055852
§ 371(c)(1), (2) Date Apr. 12, 2021,
PCT Pub. No. WO2020/077219, PCT Pub. Date Apr. 16, 2020.
Claims priority of provisional application 62/744,912, filed on Oct. 12, 2018.
Prior Publication US 2022/0125402 A1, Apr. 28, 2022
Int. Cl. A61B 8/08 (2006.01); A61B 8/00 (2006.01); A61B 8/06 (2006.01)
CPC A61B 8/0816 (2013.01) [A61B 8/06 (2013.01); A61B 8/4227 (2013.01); A61B 8/488 (2013.01); A61B 8/5223 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A method of evaluating cerebrovascular function of a patient during exercise for an exercise duration at an exercise intensity, the method comprising:
introducing a mental stimulus to the patient during the exercise duration;
collecting cerebrovascular information including measuring a MCAv from the patient during the exercise duration and mental stimulus using an ultrasonic transducer;
collecting cardiovascular information from the patient during the exercise duration and mental stimulus;
correlating the cerebrovascular information to the cardiovascular information to create a correlated cerebrovascular curve; and
determining a cerebrovascular health and viability for cerebrovascular therapy.