| CPC G06T 11/008 (2013.01) [G06V 10/25 (2022.01); G06V 10/457 (2022.01); G06V 10/476 (2022.01); G06V 10/771 (2022.01); G06V 10/7715 (2022.01); G06T 2211/424 (2013.01)] | 22 Claims |

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1. A method for generating a skeleton in an image of a cavity of an organ of a body, the method comprising:
receiving a map of the cavity, the map comprising surface voxels and interior voxels;
generating a subset of the interior voxels that are candidate locations to be on the skeleton;
pruning the subset by removing outlier candidate locations based on at least one of an angular dispersion of generative surface voxels or a variance in location of the candidate locations;
using a geometrical model comprising a statistical model, spatially compressing the candidate locations remaining in the pruned subset;
connecting the compressed candidate locations to produce one or more centerlines of the skeleton; and
displaying at least the skeleton to user.
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