US 12,455,270 B2
Mesh for dissolution test
Kensuke Horiuchi, Hyogo (JP); Satoyo Matsuura, Osaka (JP); and Maki Okabe, Osaka (JP)
Assigned to SHIONOGI & CO., LTD., Osaka (JP)
Appl. No. 17/601,539
Filed by Shionogi & Co., Ltd., Osaka (JP)
PCT Filed Apr. 7, 2020, PCT No. PCT/JP2020/015655
§ 371(c)(1), (2) Date Oct. 5, 2021,
PCT Pub. No. WO2020/209249, PCT Pub. Date Oct. 15, 2020.
Claims priority of application No. 2019-073251 (JP), filed on Apr. 8, 2019.
Prior Publication US 2022/0178901 A1, Jun. 9, 2022
Int. Cl. G01N 33/15 (2006.01); G01N 13/00 (2006.01); B01F 21/10 (2022.01)
CPC G01N 33/15 (2013.01) [G01N 13/00 (2013.01); B01F 21/10 (2022.01); B01L 2300/0609 (2013.01); G01N 2013/006 (2013.01)] 8 Claims
OG exemplary drawing
 
1. A method of preventing coning of a suspension or a solid dosage form selected from the group consisting of a suspension, a syrup, a tablet, a capsule, a granule and a pill in a dissolution test of the suspension or the solid dosage form, the method comprising:
using one single-layer mesh for the test,
placing the one single-layer mesh under a bottom of a blade and above a bottom of a vessel in a dissolution test assembly comprising the vessel used in the dissolution test, and a paddle comprising the blade and a shaft, wherein the paddle has a rotating speed of 10 to 30 rpm, and
placing the suspension or the solid dosage form on the one single-layer mesh.