US 12,454,699 B2
Downy mildew resistant melon plants
Karin Ingeborg Posthuma, Enkhuizen (NL); Laura Naranjo Peña, Enkhuizen (NL); Simon Aigner, Enkhuizen (NL); Wilhelmina Antonia Cornelia Anna Leijten, Enkhuizen (NL); and Christianus Cornelis Nicolaas Van Schie, Amsterdam (NL)
Assigned to Enza Zaden Beheer B.V., Enkhuizen (NL)
Appl. No. 17/614,117
Filed by Enza Zaden Beheer B.V., Enkhuizen (NL)
PCT Filed May 24, 2019, PCT No. PCT/EP2019/063454
§ 371(c)(1), (2) Date Nov. 24, 2021,
PCT Pub. No. WO2020/239186, PCT Pub. Date Dec. 3, 2020.
Prior Publication US 2022/0228163 A1, Jul. 21, 2022
Int. Cl. C12N 15/82 (2006.01); A01H 1/00 (2006.01); A01H 6/34 (2018.01); C12N 9/12 (2006.01)
CPC C12N 15/8282 (2013.01) [A01H 1/1255 (2021.01); A01H 6/344 (2018.05); C12N 9/1205 (2013.01); C12Y 207/01039 (2013.01)] 20 Claims
 
1. A downy mildew resistant melon plant, wherein a genome of said melon plant comprises a homoserine kinase gene expressing a mutated homoserine kinase protein, wherein the mutated homoserine kinase protein comprises an amino acid substitution of an amino acid alanine (A) to an amino acid threonine (T) at position 349 of a homoserine kinase protein having the amino acid sequence set forth in SEQ ID NO: 1.