| CPC C12M 25/18 (2013.01) [C12M 23/46 (2013.01); C12M 33/18 (2013.01)] | 17 Claims |

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1. An apparatus for use with a cell culture system, comprising:
a structured fixed bed comprising a plurality of layers of material adjacent to each other; and
a removable sample portion for recovering a sample of cells from the cell culture system;
wherein the removable sample portion comprises a perforated or pre-cut portion of one of the plurality of layers of the structured fixed bed.
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