US 12,454,510 B2
Isophthalamide compound and use thereof
Lixin Zhang, Shenyang (CN); Jing Zhang, Shenyang (CN); Hongyan Pei, Shenyang (CN); Jie Wang, Shenyang (CN); Zhubo Sheng, Shenyang (CN); and Zhuo Kang, Shenyang (CN)
Assigned to METISA BIOTECHNOLOGY CO., LTD, Nanning (CN)
Appl. No. 17/638,724
Filed by METISA BIOTECHNOLOGY CO., LTD, Nanning (CN)
PCT Filed Aug. 24, 2020, PCT No. PCT/CN2020/110706
§ 371(c)(1), (2) Date Feb. 25, 2022,
PCT Pub. No. WO2021/036965, PCT Pub. Date Mar. 4, 2021.
Claims priority of application No. 201910789623.4 (CN), filed on Aug. 26, 2019; and application No. 202010013008.7 (CN), filed on Jan. 7, 2020.
Prior Publication US 2023/0065544 A1, Mar. 2, 2023
Int. Cl. C07D 213/26 (2006.01); A01N 37/22 (2006.01); A01N 43/40 (2006.01); C07C 255/42 (2006.01); C07D 213/16 (2006.01); C07D 213/82 (2006.01); C07D 213/84 (2006.01)
CPC C07D 213/26 (2013.01) [A01N 37/22 (2013.01); A01N 43/40 (2013.01); C07C 255/42 (2013.01); C07D 213/16 (2013.01); C07D 213/82 (2013.01); C07D 213/84 (2013.01)] 10 Claims
 
1. An isophthalamide compound, wherein the isophthalamide compound has a structure shown by formula I:

OG Complex Work Unit Chemistry
In the formula I:
R1 is selected from halogen;
R2 is selected from halogen, C1-C4 halogenoalkyl, and C1-C4 halogenoalkoxy;
R3 is CF3 or CF2CF3;
R4 is selected from cyano C1-C4 alkyl;
R5 is selected from fluorine, difluoromethyl, and trifluoromethyl.