| CPC B01L 3/5021 (2013.01) [B01L 3/502715 (2013.01); B01L 2200/10 (2013.01); B01L 2300/087 (2013.01)] | 15 Claims |

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1. A functionally closed system centrifuge tube that comprises:
an inner centrifuge tube comprising:
a main loading port;
a pellet accumulation zone at a terminus of an acute-angled elbow joint;
one or more pellet removal ports disposed on a same surface as the main loading port and located distal to the acute-angled elbow joint; and
a microchannel embedded in side walls that connects the pellet accumulation zone through the acute-angled elbow joint to the one or more pellet removal ports.
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