US 12,453,858 B2
Neuromodulatory methods for improving addiction using multi-dimensional feedback
Ali Rezai, Morgantown, WV (US); Victor Finomore, Morgantown, WV (US); James Mahoney, Morgantown, WV (US); and Marc Haut, Morgantown, WV (US)
Assigned to WEST VIRGINIA UNIVERSITY BOARD OF GOVERNORS ON BEHALF OF WEST VIRGINIA UNIVERSITY, Morgantown, WV (US)
Filed by West Virginia University Board of Governors on behalf of West Virginia University, Morgantown, WV (US)
Filed on Dec. 2, 2020, as Appl. No. 17/110,152.
Claims priority of provisional application 62/942,349, filed on Dec. 2, 2019.
Claims priority of provisional application 62/942,343, filed on Dec. 2, 2019.
Claims priority of provisional application 62/942,328, filed on Dec. 2, 2019.
Prior Publication US 2021/0162216 A1, Jun. 3, 2021
Int. Cl. A61N 1/36 (2006.01); A61N 2/00 (2006.01); A61N 7/00 (2006.01)
CPC A61N 1/36089 (2013.01) [A61N 1/3615 (2013.01); A61N 1/36175 (2013.01); A61N 2/006 (2013.01); A61N 7/00 (2013.01); A61N 2007/0026 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method of improving addiction to an addictive behavior or addictive chemical substance in a patient in need thereof comprising:
obtaining a measurement of baseline values of a physiological, a cognitive, a psychosocial, and a behavioral parameter of the patient; applying an initial focused ultrasound signal, an initial deep brain stimulation signal, or an initial transcranial magnetic stimulation signal to a neural target site of the patient;
obtaining a subsequent measurement of resultant values of the physiological, the cognitive, the psychosocial, and the behavioral parameter of the patient during or after application of the initial focused ultrasound signal, the initial deep brain stimulation signal, or the initial transcranial magnetic stimulation signal;
obtaining a comparison of the resultant values to the baseline values to determine if the patient's addiction has improved; and
applying or adjusting application of one or more subsequent focused ultrasound signals, deep brain stimulation signals, transcranial magnetic stimulation signals to the neural target site upon a determination that the patient's addiction has not improved to improve the patient's addiction.