US 12,453,852 B2
Adaptive deep brain stimulation using movement desynchronization
Scott R. Stanslaski, Shoreview, MN (US); Timothy R. Abraham, Lino Lakes, MN (US); Thomas Adamski, Lake Elmo, MN (US); Timothy J. Denison, Oxford (GB); and Robert S. Raike, Minneapolis, MN (US)
Assigned to Medtronic, Inc., Minneapolis, MN (US)
Filed by Medtronic, Inc., Minneapolis, MN (US)
Filed on Oct. 27, 2023, as Appl. No. 18/384,809.
Application 18/384,809 is a continuation of application No. 17/097,776, filed on Nov. 13, 2020, granted, now 11,975,187.
Application 17/097,776 is a continuation of application No. 15/714,867, filed on Sep. 25, 2017, granted, now 10,960,202, issued on Mar. 30, 2021.
Claims priority of provisional application 62/400,605, filed on Sep. 27, 2016.
Prior Publication US 2024/0058600 A1, Feb. 22, 2024
Int. Cl. A61N 1/36 (2006.01); A61B 5/00 (2006.01); A61B 5/24 (2021.01); A61B 5/374 (2021.01); A61N 1/05 (2006.01); A61N 1/372 (2006.01); A61N 1/04 (2006.01)
CPC A61N 1/0534 (2013.01) [A61B 5/24 (2021.01); A61B 5/374 (2021.01); A61B 5/4836 (2013.01); A61B 5/4848 (2013.01); A61B 5/686 (2013.01); A61B 5/6868 (2013.01); A61N 1/36064 (2013.01); A61N 1/36067 (2013.01); A61N 1/36071 (2013.01); A61N 1/36082 (2013.01); A61N 1/36132 (2013.01); A61N 1/36135 (2013.01); A61N 1/36139 (2013.01); A61N 1/37247 (2013.01); A61B 5/0002 (2013.01); A61N 1/0476 (2013.01); A61N 1/36014 (2013.01); A61N 1/36096 (2013.01)] 25 Claims
OG exemplary drawing
 
1. An external programming device for adjusting electrical stimulation therapy delivered to a patient, the external programming device comprising:
a user interface configured to display information related to delivery of the electrical stimulation therapy and to receive user input;
a telemetry module configured to communicate between the user interface and an implantable medical device implanted in the patient, wherein the implantable medical device is configured to deliver electrical stimulation therapy to a tissue of a patient via one or more electrodes;
a processor; and
a memory storing data for processing by the processor, the data, when processed, causing the processor to:
receive a first user input from a clinician to define a first homeostatic window having an upper bound and a lower bound related to sensed response signals received during electrical stimulation therapy delivered to the tissue of the patient and a second therapeutic window having an upper bound and a lower bound related to a magnitude of at least one parameter of the electrical stimulation therapy,
receive a first sensed response signal of the patient during the delivery of the electrical stimulation therapy,
sense at least one of a posture and activity change associated with the patient,
adjust the magnitude of the at least one parameter of the electrical stimulation therapy based on the sensing the at least one of the posture and activity change associated with the patient, wherein the magnitude of the at least one parameter is at least one of incrementally increased or incrementally decreased within the second therapeutic window,
receive feedback corresponding to a feeling of paresthesia experienced by the patient in response to the electrical stimulation therapy, and
shift a position of the first homeostatic window based on the paresthesia feedback.