US 12,453,812 B2
Integrated system for mechanical processing of lipoaspirate
Jered Haun, Irvine, CA (US); and Jeremy A. Lombardo, Irvine, CA (US)
Assigned to THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US)
Appl. No. 17/617,301
Filed by THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US)
PCT Filed Jun. 23, 2020, PCT No. PCT/US2020/039187
§ 371(c)(1), (2) Date Dec. 7, 2021,
PCT Pub. No. WO2020/263858, PCT Pub. Date Dec. 30, 2020.
Claims priority of provisional application 62/865,749, filed on Jun. 24, 2019.
Prior Publication US 2022/0249761 A1, Aug. 11, 2022
Int. Cl. A61M 1/00 (2006.01); A61K 35/35 (2015.01); B01L 3/00 (2006.01)
CPC A61M 1/892 (2021.05) [A61K 35/35 (2013.01); B01L 3/50273 (2013.01); B01L 3/502753 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0864 (2013.01)] 10 Claims
OG exemplary drawing
 
1. An emulsification device for processing lipoaspirate comprising:
a substrate having an inlet and an outlet and a fluid passageway extending between the inlet and the outlet;
a first constriction region formed in the fluid passageway adjacent to the inlet;
a second constriction region formed in the fluid passageway adjacent to the outlet; and
an expansion region formed in the fluid passageway between the first constriction region and the second constriction region, wherein the expansion region is formed in multiple planes, such that an angled wall or a surface of the expansion region extends in three dimensions, and the expansion region is configured for turbulent mixing; and
wherein the first constriction region and the second constriction region have a cross-sectional dimension of between 0.5 mm and 4 mm and wherein the expansion region has a maximum cross-sectional dimension within the range of range of about 5 mm to about 30 mm.