US 12,453,807 B2
Extracorporeal oxygenation system for low flow rates and methods of use
Dagi Ben Noon, Burgata (IL); and Abraham Shabtay, Tel-Aviv (IL)
Assigned to INSPIRA-TECHNOLOGIES OXY B.H.N. LTD., Ra'anana (IL)
Filed by Inspira-Technologies OXY B.H.N. LTD., Ra'anana (IL)
Filed on Jun. 29, 2023, as Appl. No. 18/216,565.
Application 18/216,565 is a division of application No. 17/905,413, granted, now 11,793,919, previously published as PCT/IL2021/051431, filed on Dec. 1, 2021.
Claims priority of provisional application 63/123,809, filed on Dec. 10, 2020.
Claims priority of provisional application 63/167,226, filed on Mar. 29, 2021.
Claims priority of provisional application 63/119,997, filed on Dec. 1, 2020.
Prior Publication US 2023/0338634 A1, Oct. 26, 2023
Int. Cl. A61M 1/16 (2006.01); A61M 1/14 (2006.01); A61M 1/26 (2006.01); A61M 1/30 (2006.01); A61M 1/32 (2006.01); A61M 1/36 (2006.01); A61M 5/00 (2006.01); A61M 5/158 (2006.01); A61M 5/168 (2006.01); A61M 5/36 (2006.01); A61M 5/14 (2006.01)
CPC A61M 1/1698 (2013.01) [A61M 1/14 (2013.01); A61M 1/15 (2022.05); A61M 1/155 (2022.05); A61M 1/1611 (2014.02); A61M 1/267 (2014.02); A61M 1/30 (2013.01); A61M 1/32 (2013.01); A61M 1/3609 (2014.02); A61M 1/3622 (2022.05); A61M 1/36225 (2022.05); A61M 1/362262 (2022.05); A61M 1/3629 (2014.02); A61M 1/3643 (2013.01); A61M 1/3644 (2014.02); A61M 1/3646 (2014.02); A61M 1/3647 (2014.02); A61M 5/002 (2013.01); A61M 5/1582 (2013.01); A61M 5/16886 (2013.01); A61M 5/36 (2013.01); A61M 2005/006 (2013.01); A61M 2005/1402 (2013.01); A61M 2205/3306 (2013.01); A61M 2205/3331 (2013.01); A61M 2205/3334 (2013.01); A61M 2205/3368 (2013.01); A61M 2205/707 (2013.01)] 16 Claims
OG exemplary drawing
 
9. A method for supporting a patient having a low blood oxygen saturation level to allow for spontaneous breathing by the patient, the method comprising:
preparing an extracorporeal blood circulation path for integration with a patient's vascular system;
coupling said patient's vascular system to said extracorporeal blood circulation path, wherein said extracorporeal blood circulation path is incorporated into a blood oxygenation system comprising sensors and a controller;
receiving input of patient parameters from the sensors to the controller;
configuring the controller to modify or adjust the flow rate of blood, or other definitive aspects of the system, to obtain the desired target oxygenation level, based on the input of patient parameters;
incorporating a low flow rate oxygenator for oxygenating blood flowing therein and withdrawing CO2 therefrom; and
adjusting the flow rate of blood flowing within said extracorporeal blood circulation path not to exceed 30 ml/kg per minute and not exceed 2/5 of the patient's blood circulation rate, wherein said blood circulation rate is determined based on the patient's weight,
wherein the blood oxygenation system is a low flow rate oxygenator for oxygenating blood flowing therein and withdrawing CO2 therefrom; and
wherein the flow rate of blood flowing into said extracorporeal blood circulation path is not greater than 30 ml/kg per minute.