	US 12,453,691 B2
	Composition comprising hyaluronic acid-based polyion complex particle
Toshifumi Shiroya, Kawasaki (JP); Tatsushi Isojima, Kawasaki (JP); Mariko Yamamoto, Kawasaki (JP); Takehiko Kasai, Kawasaki (JP); Kazuhiko Maruyama, Kawasaki (JP); and Shinobu Mitsuda, Kawasaki (JP)
Assigned to L'Oreal, Paris (FR)
Appl. No. 17/785,019
Filed by L'Oreal, Paris (FR)
PCT Filed Dec. 4, 2020, PCT No. PCT/JP2020/046188 § 371(c)(1), (2) Date Jun. 13, 2022, PCT Pub. No. WO2021/125069, PCT Pub. Date Jun. 24, 2021.
Claims priority of application No. 2019-227501 (JP), filed on Dec. 17, 2019.
Prior Publication US 2023/0051904 A1, Feb. 16, 2023
Int. Cl. A61K 8/73 (2006.01); A61K 8/34 (2006.01); A61K 8/55 (2006.01); A61K 8/64 (2006.01); A61Q 19/00 (2006.01)

CPC A61K 8/735 (2013.01) [A61K 8/34 (2013.01); A61K 8/55 (2013.01); A61K 8/64 (2013.01); A61Q 19/007 (2013.01); A61K 2800/5424 (2013.01); A61K 2800/5426 (2013.01); A61K 2800/5428 (2013.01); A61K 2800/95 (2013.01)]

16 Claims

1. A composition, comprising:

(a) at least one particle, comprising

at least one cationic polymer and at least one anionic polymer,

at least one cationic polymer and at least one amphoteric polymer,

at least one anionic polymer and at least one amphoteric polymer, or

at least one amphoteric polymer, and

at least one non-polymeric acid having two or more pKa values or salt(s) thereof or

at least one non-polymeric base having two or more pKb values or salt(s) thereof; and

(b) water, wherein

the anionic polymer is selected from hyaluronic acid, and esters and salts thereof, and

the amphoteric polymer is selected from cationized hyaluronic acid and salts thereof.