US 12,453,631 B2
Collapsible-expandable heart valves
Brian S. Conklin, Orange, CA (US)
Assigned to EDWARDS LIFESCIENCES CORPORATION, Irvine, CA (US)
Filed by Edwards Lifesciences Corporation, Irvine, CA (US)
Filed on Dec. 22, 2021, as Appl. No. 17/645,690.
Application 14/466,912 is a division of application No. 13/237,556, filed on Sep. 20, 2011, granted, now 8,845,720, issued on Sep. 30, 2014.
Application 17/645,690 is a continuation of application No. 16/989,826, filed on Aug. 10, 2020, granted, now 11,207,178, issued on Dec. 28, 2021.
Application 16/989,826 is a continuation of application No. 15/864,992, filed on Jan. 8, 2018, granted, now 10,736,741, issued on Aug. 11, 2020.
Application 15/864,992 is a continuation of application No. 14/466,912, filed on Aug. 22, 2014, granted, now 9,861,479, issued on Jan. 9, 2018.
Claims priority of provisional application 61/472,083, filed on Apr. 5, 2011.
Claims priority of provisional application 61/386,833, filed on Sep. 27, 2010.
Prior Publication US 2022/0110743 A1, Apr. 14, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 2/24 (2006.01)
CPC A61F 2/243 (2013.01) [A61F 2/24 (2013.01); A61F 2/2412 (2013.01); A61F 2/2415 (2013.01); A61F 2/2418 (2013.01); A61F 2/2433 (2013.01); A61F 2220/0075 (2013.01); A61F 2230/0054 (2013.01); A61F 2250/0036 (2013.01); A61F 2250/006 (2013.01); A61F 2250/0071 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A prosthetic heart valve for implant at a patient's aortic annulus having a fibrous shelf between an upstream left ventricle and a downstream aorta, comprising:
a collapsible-expandable one-piece frame having a stent portion and a leaflet support portion, the frame being formed of material that permits radial collapse to a collapsed state having a small profile for delivery to the annulus and which enables elastic self-expansion from the collapsed state to an expanded state, the leaflet support portion being positioned along an axis at an outflow end of the frame in series with the stent portion at an inflow end, the leaflet support portion having around a frame periphery a continuous structure formed of elongate members defining three alternating arcuate cusps curved toward the inflow end and three upstanding commissure supports projecting toward the outflow end and terminating in arcuate commissure tips, the leaflet support portion having a cloth covering extending along the cusps and commissure supports, wherein the stent portion comprises a plurality of axially-oriented struts spaced around the frame periphery and connected by a plurality of rows of collapsible-expandable bent struts that allow the stent portion to radially collapse to a compressed configuration for delivery and facilitate expansion of the stent portion so as to engage the inner periphery of the body lumen, wherein three of the axially-oriented struts couple the stent portion to the leaflet support portion, and wherein the axially-oriented struts that couple the stent portion to the leaflet support portion are aligned with and couple directly to the upstanding commissure supports of the leaflet support portion; and
three flexible bioprosthetic leaflets each having an arcuate cusp portion between two commissure portions, each arcuate cusp portion being co-extensive and secured to the cloth covering around one of the leaflet support portion cusps, and each commissure portion having a tab, wherein the tabs of each adjacent leaflet pair are brought together and secured to one of the upstanding commissure supports of the leaflet support portion, and wherein
the stent portion is configured to engage an inner periphery of a body lumen at the aortic annulus implantation site with the commissure supports being cantilevered into the aorta.