| CPC A61B 5/685 (2013.01) [A61B 5/0022 (2013.01); A61B 5/14514 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/14865 (2013.01); A61B 5/6833 (2013.01); A61B 5/742 (2013.01); G01N 27/327 (2013.01)] | 33 Claims | 

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               1. A microneedle array for use in sensing a first analyte and a second analyte, comprising: 
            a first microneedle comprising a first working electrode comprising a first biorecognition element configured to react with the first analyte, wherein the first biorecognition element is entrapped within a first biorecognition layer comprising a first conducting polymer, wherein a distal tip of the first microneedle is formed from a semiconducting material and comprises an insulating layer on the semiconducting material, and wherein a distal edge of the first working electrode is offset from the distal tip; and 
                a second microneedle comprising a second working electrode comprising a second biorecognition element configured to react with the second analyte, wherein the second biorecognition element is entrapped within a second biorecognition layer comprising a second conducting polymer, wherein a distal tip of the second microneedle is formed from a semiconducting material and comprises an insulating layer on the semiconducting material, and wherein a distal edge of the second working electrode is offset from the distal tip, 
                wherein the first analyte and the second analyte are different. 
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