US 12,453,512 B2
Tumor ablation planning using interstitial optical mapping
Matthew W. Koenig, Denver, CO (US)
Assigned to Medtronic Navigation, Inc., Louisville, CO (US)
Filed by Medtronic Navigation, Inc., Louisville, CO (US)
Filed on Jul. 7, 2021, as Appl. No. 17/369,495.
Claims priority of provisional application 63/061,933, filed on Aug. 6, 2020.
Prior Publication US 2022/0039744 A1, Feb. 10, 2022
Int. Cl. A61B 5/00 (2006.01); A61B 5/055 (2006.01); A61B 18/24 (2006.01); A61B 18/00 (2006.01); A61B 18/20 (2006.01)
CPC A61B 5/4887 (2013.01) [A61B 5/0035 (2013.01); A61B 5/0036 (2018.08); A61B 5/0071 (2013.01); A61B 5/0084 (2013.01); A61B 5/055 (2013.01); A61B 5/7425 (2013.01); A61B 18/24 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/2005 (2013.01)] 19 Claims
OG exemplary drawing
 
1. An optical tumor mapping system, comprising:
an emitter optical fiber configured to emit light;
an imaging optical fiber configured to receive light, wherein the emitter optical fiber and the imaging optical fiber are configured to be selectively slidingly disposed within a catheter; and
a processor configured to:
generate, via the light received by the imaging optical fiber as the emitter optical fiber and the imaging optical fiber are moved along the catheter, a computerized representation of a margin of a target tissue structure,
wherein the light received by the imaging optical fiber is received while the emitter optical fiber and the imaging optical fiber are at a first position within the catheter and at a second position within the catheter, while the catheter penetrates entirely through the target tissue structure,
wherein the first position is at a distal end of the catheter that has penetrated entirely through the target tissue structure such that, in the first position, the imaging optical fiber and the emitter optical fiber are in a region of the catheter that is outside the target tissue structure,
wherein the second position is further away from the distal end of the catheter than the first position such that, in the second position, the imaging optical fiber and the emitter optical fiber are in a region of the catheter that is within the target tissue structure, and
wherein the processor is configured to perform a spectral analysis on the light received by the imaging optical fiber at the first position and the second position to generate the computerized representation of the margin of the target tissue structure, and to identify non-cancerous tissue; and
generate a laser ablation plan to guide a laser ablation procedure based on the computerized representation of the margin of the target tissue structure and the identified non-cancerous tissue.