US 12,453,494 B1
Methods and systems for measuring glucose having improved decay rates and lag times
Paul V. Goode, Temple, TX (US); Mark Allan Tapsak, Front Royal, VA (US); James Patrick Thrower, Bethesda, MD (US); and Peter Koziar, Jr., Lititz, PA (US)
Filed by Glucotrack, Inc., Rutherford, NJ (US)
Filed on Apr. 11, 2025, as Appl. No. 19/177,166.
Claims priority of provisional application 63/661,648, filed on Jun. 19, 2024.
Claims priority of provisional application 63/633,647, filed on Apr. 12, 2024.
Int. Cl. A61B 5/1486 (2006.01); A61B 5/145 (2006.01)
CPC A61B 5/14532 (2013.01) [A61B 5/14865 (2013.01)] 13 Claims
OG exemplary drawing
 
1. An enzymatic electrochemical glucose sensor adapted to be at least partially positioned within a fluid-filled lumen of a biological host and configured to generate data indicative of a glucose level of the biological host, comprising:
a lead assembly configured to extend into said fluid-filled lumen, wherein the lead assembly comprises at least one electrode and a membrane positioned over the electrode and wherein the at least one electrode is configured to generate a current, and wherein the current is indicative of, and responsive to, the glucose level of the biological host; and,
an electronics assembly, comprising a potentiostat and a digital subassembly, wherein the electronics assembly is configured to connect to a proximal end of the lead assembly and be in electrical communication with the at least one electrode, wherein the potentiostat is configured to apply a bias potential to generate the current at the lead assembly, to receive the current from the lead assembly, and to convert the current into an analog voltage signal, and wherein the digital subassembly is configured to receive the analog voltage signal from the potentiostat and to apply an adaptive gain to said analog voltage signal to generate an adaptive gain signal wherein the applied adaptive gain is based on changes to the current, and wherein the adaptive gain is increased by a first predetermined amount when the current falls below a first predetermined level over a first time period and is increased by a second predetermined amount when the current falls below a second predetermined level over a second time period.