US 12,453,477 B2
Endoscopic imaging using nanoscale metasurfaces
Hamid Pahlevaninezhad, Cambridge, MA (US); Mohammadreza Khorasaninejad, Cambridge, MA (US); Yao-Wei Huang, Cambridge, MA (US); Zhujun Shi, Cambridge, MA (US); Melissa Suter, Cambridge, MA (US); and Federico Capasso, Cambridge, MA (US)
Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US); THE GENERAL HOSPITAL CORPORATION, Boston, MA (US); and PARTNERS HEALTHCARE, Cambridge, MA (US)
Appl. No. 16/772,644
Filed by PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US); THE GENERAL HOSPITAL CORPORATION, Boston, MA (US); and PARTNERS HEALTHCARE, Cambridge, MA (US)
PCT Filed Dec. 12, 2018, PCT No. PCT/US2018/065288
§ 371(c)(1), (2) Date Jun. 12, 2020,
PCT Pub. No. WO2019/118646, PCT Pub. Date Jun. 20, 2019.
Claims priority of provisional application 62/598,455, filed on Dec. 13, 2017.
Prior Publication US 2021/0068665 A1, Mar. 11, 2021
Int. Cl. A61B 5/00 (2006.01); A61B 1/00 (2006.01); A61B 1/07 (2006.01); G01B 9/02001 (2022.01); G01B 9/02091 (2022.01); G02B 1/00 (2006.01); G02B 3/00 (2006.01); G02B 23/24 (2006.01); G02B 27/00 (2006.01)
CPC A61B 5/0097 (2013.01) [A61B 1/00096 (2013.01); A61B 1/00188 (2013.01); A61B 1/07 (2013.01); A61B 5/0066 (2013.01); A61B 5/0068 (2013.01); G01B 9/02001 (2013.01); G01B 9/02091 (2013.01); G02B 1/002 (2013.01); G02B 3/0087 (2013.01); G02B 23/243 (2013.01); G02B 27/0025 (2013.01); A61B 1/00165 (2013.01); G02B 2207/101 (2013.01)] 25 Claims
OG exemplary drawing
 
1. An endoscopic imaging device, comprising:
a light-transmitting tubing;
at least one optical fiber disposed in the light-transmitting tubing; and
at least one metalens optically coupled to the optical fiber and configured to:
receive light from the optical fiber;
transmit the light through the at least one metalens; and
focus the light from the optical fiber, through the light-transmitting tubing, and to a target point located outside of the light-transmitting tubing;
wherein the metalens includes a plurality of nanostructures, and the nanostructures define a phase profile that corrects one or more aberrations including astigmatism caused by the light-transmitting tubing;
wherein the phase profile corrects the one or more aberrations by focusing the light from the optical fiber to a diffraction-limited spot; and
wherein the phase profile, φ, is a function of Lsl which is an optical path length between a facet of the optical fiber and the metalens, Llf which is an optical path length between the metalens and a focal point of the metalens, and Lchief which is an optical path length of a chief ray.