US 12,123,932 B2
System and method for quantitative mapping with magnetic resonance imaging
Daiki Tamada, Madison, WI (US); and Scott B. Reeder, Middleton, WI (US)
Assigned to WISCONSIN ALUMNI RESEARCH FOUNDATION, Madison, WI (US)
Filed by Wisconsin Alumni Research Foundation, Madison, WI (US)
Filed on Apr. 2, 2021, as Appl. No. 17/221,280.
Prior Publication US 2022/0326327 A1, Oct. 13, 2022
Int. Cl. G01R 33/48 (2006.01); G01R 33/36 (2006.01); G01R 33/44 (2006.01); G01R 33/561 (2006.01); G01R 33/565 (2006.01)
CPC G01R 33/4828 (2013.01) [G01R 33/3621 (2013.01); G01R 33/445 (2013.01); G01R 33/5615 (2013.01); G01R 33/56518 (2013.01); G01R 33/56554 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A magnetic resonance imaging (MRI) system comprising:
a magnet system configured to generate a static magnetic field (B0) about at least a portion of a subject arranged in the MRI system;
a plurality of gradient coils configured to apply magnetic gradients to the polarizing magnetic field;
a radio frequency (RF) system configured to apply an excitation field to the subject and acquire MR image data from the subject;
a computer system programmed to:
control the plurality of gradient coils and the RF system to perform a gradient echo pulse sequence that includes a phase increment of an RF pulse of the gradient echo pulse sequence selected to induce a phase difference between two echoes selected to be similar, other than echo time (TE);
control the RF system to acquire MR data corresponding to at least the two echoes selected to be similar, other than TE;
derive a B0 map using the MR data corresponding to the two echoes selected to be similar, other than TE; and
use the B0 map and MR data from at least one of the two echoes selected to be similar, other than TE, generate a map of T2 of the subject.