US 12,122,988 B2
Cell evaluation device and cell evaluation system
Shiori Oshima, Kanagawa (JP); Koji Futamura, Tokyo (JP); Kenji Tanaka, Tokyo (JP); Tomoyuki Umetsu, Tokyo (JP); and Masahiro Matsumoto, Kanagawa (JP)
Assigned to SONY CORPORATION, Tokyo (JP)
Appl. No. 16/978,153
Filed by SONY CORPORATION, Tokyo (JP)
PCT Filed Jan. 17, 2019, PCT No. PCT/JP2019/001252
§ 371(c)(1), (2) Date Sep. 3, 2020,
PCT Pub. No. WO2019/176275, PCT Pub. Date Sep. 19, 2019.
Claims priority of application No. 2018-044776 (JP), filed on Mar. 12, 2018.
Prior Publication US 2021/0040426 A1, Feb. 11, 2021
Int. Cl. C12M 1/34 (2006.01); G01N 21/76 (2006.01)
CPC C12M 1/34 (2013.01) [G01N 21/76 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A cell evaluation device, comprising:
a first capturing device configured to capture a secretory substance secreted by cells, wherein
the first capturing device includes a first molecule that is nonspecifically bonded to the secretory substance, and
the first molecule is at least one selected from a group consisting of a first aptamer and a molecular imprinted polymer;
a second capturing device configured to capture the cells, wherein
the second capturing device includes a second molecule that is nonspecifically bonded to the cells, and
the second molecule is at least one selected from a group consisting of a supramolecule and oleylamine; and
an image sensor configured to:
acquire a first image by a first imaging process of observation light of the cells and light emitted from a luminescent substance bonded to the secretory substance,
wherein the first capturing device is on the image sensor; and
acquire, based on the first image, position information of the cells and the secretory substance.