US 12,122,789 B2
Forms of pyrido[1,2-a]pyrimidin-4-one derivatives, its formulation and its process of making
Roland Meier, Basel (CH); Urs Schwitter, Basel (CH); Anne De Paepe, Basel (CH); Juergen Thun, Basel (CH); and Frank Stowasser, Basel (CH)
Assigned to Hoffmann-La Roche Inc., Little Falls, NJ (US)
Filed by Hoffmann-La Roche Inc., Little Falls, NJ (US)
Filed on Apr. 16, 2021, as Appl. No. 17/233,368.
Application 17/233,368 is a continuation of application No. PCT/EP2019/078313, filed on Oct. 18, 2019.
Claims priority of application No. 18201564 (EP), filed on Oct. 19, 2018.
Prior Publication US 2021/0403487 A1, Dec. 30, 2021
Int. Cl. C07D 519/00 (2006.01)
CPC C07D 519/00 (2013.01) [C07B 2200/13 (2013.01)] 31 Claims
 
1. A solid form of a compound of formula (I)

OG Complex Work Unit Chemistry
wherein the solid form is crystalline Form A having an x-ray powder diffraction (XRPD) pattern comprising at least two XRPD peaks selected from the group consisting of 8.3 (±0.2) degrees two-theta, 11.4 (±0.2) degrees two-theta, 15.1 (±0.2) degrees two-theta, 15.9 (±0.2) degrees two-theta, 17.0 (±0.2) degrees two-theta. 24.0 (±0.2) degrees two-theta, and 25.6 (±0.2) degrees two-theta angle of diffraction.