	US 12,121,518 B2
	PARP-1 and methods of use thereof
Hamid Boulares, New Orleans, LA (US); and Mohamed Ghonim, New Orleans, LA (US)
Assigned to THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSI AND AGRICULTURAL AND MECHANICAL COLLEGE, Baton Rouge, LA (US)
Filed by The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Baton Rouge, LA (US)
Filed on Jan. 14, 2020, as Appl. No. 16/742,625.
Application 16/742,625 is a continuation in part of application No. 16/564,735, filed on Sep. 9, 2019, granted, now 11,723,906.
Application 16/564,735 is a continuation in part of application No. PCT/US2018/021855, filed on Mar. 9, 2018.
Claims priority of provisional application 62/792,373, filed on Jan. 14, 2019.
Claims priority of provisional application 62/469,436, filed on Mar. 9, 2017.
Prior Publication US 2020/0230134 A1, Jul. 23, 2020
Int. Cl. A61K 31/502 (2006.01); A61K 31/573 (2006.01); A61K 38/00 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01)

CPC A61K 31/502 (2013.01) [A61K 31/573 (2013.01); A61P 35/00 (2018.01); C07K 16/2827 (2013.01); A61K 38/00 (2013.01)]

18 Claims

1. A composition comprising between 1 mg and 45 mg of a PARP inhibitor compound and at least two additional anti-cancer agents, wherein the at least two additional anti-cancer agents comprise a γ-secretase inhibitor and a steroid.