US 12,121,370 B2
Systems and methods of monitoring autoregulation
Dean Montgomery, Edinburgh (GB); Paul S. Addison, Edinburgh (GB); and Peter Galen, Portland, OR (US)
Assigned to COVIDIEN LP, Mansfield, MA (US)
Filed by Covidien LP, Mansfield, MA (US)
Filed on Jul. 6, 2020, as Appl. No. 16/921,416.
Application 16/921,416 is a continuation of application No. 15/648,665, filed on Jul. 13, 2017, granted, now 10,736,578.
Claims priority of provisional application 62/362,325, filed on Jul. 14, 2016.
Claims priority of provisional application 62/362,329, filed on Jul. 14, 2016.
Prior Publication US 2020/0330049 A1, Oct. 22, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/00 (2006.01); A61B 5/021 (2006.01); A61B 5/1455 (2006.01); G16H 50/30 (2018.01)
CPC A61B 5/7275 (2013.01) [A61B 5/021 (2013.01); A61B 5/14551 (2013.01); A61B 5/14553 (2013.01); A61B 5/4064 (2013.01); A61B 5/7246 (2013.01); G16H 50/30 (2018.01)] 20 Claims
OG exemplary drawing
 
1. A system for monitoring autoregulation, the system comprising:
an oxygen saturation sensor configured to obtain an oxygen saturation signal indicative of an oxygen saturation of a patient during a patient monitoring session;
one or more output devices comprising at least one of a display device or an audio device; and
a controller comprising one or more processors configured to:
receive the oxygen saturation signal;
receive a blood pressure signal indicative of a blood pressure of the patient;
determine an oxygen saturation gradient based on the oxygen saturation signal over a period of time during the patient monitoring session;
determine a blood pressure gradient based on the blood pressure signal over the period of time during the patient monitoring session;
in response to determining that at least one of an absolute value of the blood pressure gradient exceeds a blood pressure gradient threshold or an absolute value of the oxygen saturation gradient exceeds an oxygen saturation gradient threshold, determine an instantaneous autoregulation status based on a relationship between the oxygen saturation gradient and the blood pressure gradient;
in response to determining the instantaneous autoregulation status does not correspond to a previous instantaneous autoregulation status stored in a memory device, determine a confidence level of the previous instantaneous autoregulation status;
in response to determining the confidence level is above a threshold:
set the instantaneous autoregulation status to the previous instantaneous autoregulation status to generate an updated instantaneous autoregulation status; and
control the one or more output devices to output, during the patient monitoring session, an indication of the updated instantaneous autoregulation status.