US 12,121,290 B2
Electrode assembly including expandable isolation member
Troy Tegg, Elk River, MN (US); and Salo Arias, Brooklyn Park, MN (US)
Assigned to St. Jude Medical, Cardiology Division, Inc., St. Paul, MN (US)
Filed by St. Jude Medical, Cardiology Division, Inc., St. Paul, MN (US)
Filed on Dec. 22, 2020, as Appl. No. 17/247,770.
Claims priority of provisional application 62/983,200, filed on Feb. 28, 2020.
Prior Publication US 2021/0267672 A1, Sep. 2, 2021
Int. Cl. A61B 18/14 (2006.01); A61B 18/00 (2006.01)
CPC A61B 18/1492 (2013.01) [A61B 2018/0022 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00613 (2013.01)] 19 Claims
OG exemplary drawing
 
1. An electroporation system comprising:
a catheter shaft;
an electrode assembly coupled to the catheter shaft, the electrode assembly comprising:
an electrode pair comprising a first electrode and a second electrode configured to be selectively energized for delivery of electroporation therapy; and
an expandable isolation member disposed axially between the first electrode and the second electrode, wherein one of the first electrode and the second electrode is positioned proximally of a proximal end of the expandable isolation member and the other of the first electrode and the second electrode is positioned distal to a distal end of the expandable isolation member, the expandable isolation member configurable between a collapsed configuration and an expanded configuration;
wherein the expandable isolation member comprises a circumferential sealing surface configured for sealing engagement with tissue of a patient such that the expandable isolation member inhibits fluid and electrical communication between the first electrode and the second electrode when engaged with tissue of the patient; and
wherein the one of the first electrode and the second electrode positioned distal to the distal end of the expandable isolation member comprises a pair of ring electrodes separated by an insulating member, wherein the pair of ring electrodes is configured to map the tissue of the patient; and
an electroporation generator coupled in communication with the first electrode and the second electrode and configured to supply an electroporation signal thereto for the delivery of the electroporation therapy to the tissue of the patient, wherein the electroporation system is configured to:
determine a level of sealing between the circumferential sealing surface and the tissue; and
increase a voltage of the electroporation signal to be applied to the tissue based on a reduced level of sealing.