US 11,795,449 B2
Nucleic acid collection column
Shota Sekiguchi, Kamakura (JP); Takahiro Motoshiromizu, Kamakura (JP); and Masateru Ito, Kamakura (JP)
Assigned to Toray Industries, Inc., Tokyo (JP)
Appl. No. 17/283,624
Filed by Toray Industries, Inc., Tokyo (JP)
PCT Filed Oct. 30, 2019, PCT No. PCT/JP2019/042599
§ 371(c)(1), (2) Date Apr. 8, 2021,
PCT Pub. No. WO2020/090900, PCT Pub. Date May 7, 2020.
Claims priority of application No. 2018-205482 (JP), filed on Oct. 31, 2018.
Prior Publication US 2021/0340522 A1, Nov. 4, 2021
Int. Cl. C12N 15/00 (2006.01); C12N 15/10 (2006.01); B01D 15/20 (2006.01)
CPC C12N 15/1006 (2013.01) [B01D 15/206 (2013.01)] 3 Claims
OG exemplary drawing
 
1. A nucleic acid collection column for collecting a nucleic acid from a liquid sample containing the nucleic acid, comprising:
a sample injection portion having an opening into which the liquid sample containing the nucleic acid is injected;
a support adsorption portion configured to house a support that adsorbs the nucleic acid, the nucleic acid being adsorbed on the support in the support adsorption portion; and
a discharge portion configured to discharge a liquid passed through the support adsorption portion, wherein
the support includes aluminum oxide having a surface where a water-soluble neutral polymer is adsorbed,
a space that houses the support in the support adsorption portion has a cylindrical shape, and has a volume of 0.13 μL or more and 13.5 μL or less, and
an aspect ratio (d1/d2) of the space satisfies 1.0≤d1/d2<15.0, where d1 is a length in an axial direction of the space, and d2 is a diameter in a direction orthogonal to the axial direction.