CPC C07K 16/1063 (2013.01) [C07K 14/162 (2013.01); A61K 38/00 (2013.01); C07K 2317/10 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2319/02 (2013.01); C07K 2319/31 (2013.01)] | 13 Claims |
1. An isolated monoclonal antibody that specifically binds to HIV Env and comprises a VH CDR1, VH CDR2, VH CDR3, VL CDR1, VL CDR2, and VL CDR3, wherein the VH CDR3 comprises the amino acid sequence of SEQ ID NO: 3, and wherein the VH CDR1, VH CDR2, VL CDR1, VL CDR2, and VL CDR3 are from
a) NC-Cow1, NC-Cow7, NC-Cow8, NC-Cow9, or NC-Cow10; or
b) germline reverted NC-Cow1.
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