US 11,794,161 B1
Reduced permeability microcapsules
Jiten Dihora, Center Valley, PA (US); and Praveen Bachawala, Allentown, PA (US)
Assigned to TRUCAPSOL, LLC, Bethlehem, PA (US)
Filed by TRUCAPSOL, LLC, Bethlehem, PA (US)
Filed on Nov. 13, 2019, as Appl. No. 16/682,862.
Claims priority of provisional application 62/770,251, filed on Nov. 21, 2018.
Int. Cl. B01J 13/16 (2006.01); C11D 17/00 (2006.01); A61K 9/50 (2006.01); A01N 25/28 (2006.01); A23L 2/00 (2006.01); A23L 27/00 (2016.01)
CPC B01J 13/16 (2013.01) [C11D 17/0039 (2013.01); A01N 25/28 (2013.01); A23L 27/72 (2016.08); A61K 9/5026 (2013.01); A61K 9/5073 (2013.01)] 22 Claims
 
1. A composition comprising controlled release particles, wherein each of the controlled release particles comprises:
(a) a core comprising at least one hydrophobic active ingredient; and
(b) a wall at least partially surrounding the core and comprising:
(i) an outer layer comprising a reaction product of an amine and an isocyanate;
(ii) an intermediate layer under the outer layer and comprising a reaction product of an acid and an isocyanate;
(iii) an inner layer under the intermediate layer and comprising an acrylate copolymer; and optionally
(iv) an optional outer layer above the outer layer and comprising a quaternary amine containing moiety,
wherein the core is switchable from a low viscosity liquid to a semisolid without using high melting point waxes or polymers, and the controlled release particles are effective to retain the at least one hydrophobic active ingredient upon exposure to water and effective to release the at least one hydrophobic active ingredient in response to friction.