US 11,793,893 B2
Compounds comprising conductive oligomers, materials formed therefrom, and methods of making and using same
Jian Yang, Arlington, TX (US); and Dingying Shan, University Park, PA (US)
Assigned to THE PENN STATE RESEARCH FOUNDATION, University Park (PA)
Appl. No. 16/337,469
Filed by THE PENN STATE RESEARCH FOUNDATION, University Park, PA (US)
PCT Filed Oct. 3, 2017, PCT No. PCT/US2017/055003
§ 371(c)(1), (2) Date Mar. 28, 2019,
PCT Pub. No. WO2018/067617, PCT Pub. Date Apr. 12, 2018.
Claims priority of provisional application 62/525,821, filed on Jun. 28, 2017.
Claims priority of provisional application 62/403,224, filed on Oct. 3, 2016.
Prior Publication US 2019/0231909 A1, Aug. 1, 2019
Int. Cl. A61K 49/22 (2006.01); C08G 63/685 (2006.01); A61K 31/215 (2006.01); C08G 63/91 (2006.01); A61B 5/00 (2006.01); A61K 49/00 (2006.01)
CPC A61K 49/222 (2013.01) [A61B 5/0095 (2013.01); A61K 31/215 (2013.01); A61K 49/005 (2013.01); C08G 63/6854 (2013.01); C08G 63/91 (2013.01)] 15 Claims
 
1. A compound having a structure:

OG Complex Work Unit Chemistry
wherein
A is an aliphatic group,
R1 is in each case independently selected from:
i) H;
ii) a biocompatible multifunctional carboxylic acid moiety covalently bonded to a conductive oligomer group/moiety;
iii) a biocompatible multifunctional carboxylic acid group covalently bonded to a polyol; and
iv) a biocompatible multifunctional carboxylic acid group;
v) a linker moiety/group,
vi) a linker moiety covalently bonded to a conductive oligomer group/moiety, and/or a polyol group/moiety;
R2 is independently selected from:
i) —OH,
ii) a polyol group,
iii) a conductive oligomer group,
iv) a polyol moiety covalently bonded to a biocompatible multifunctional carboxylic acid group,
v) a polyol covalently bonded to a biocompatible multifunctional carboxylic acid group, said biocompatible multifunctional carboxylic acid group being covalently bonded to one or more of a conductive oligomer group, a linker group, a biocompatible multifunctional carboxylic acid group, or polyol group;
vi) a polyol covalently bonded to a linker group said linker group being covalently bonded to one or more of a conductive oligomer group, a linker group, biocompatible multifunctional carboxylic acid group, or polyol group;
wherein the compound comprises an oligomer covalently bonded to one or more conductive oligomeric groups, wherein the conductive oligomeric group is aniline tetramer.