US 11,793,790 B2
Compositions against Candida infections
Bruno Cammue, Alsemberg (BE); Karin Thevissen, Bierbeek (BE); Kaat De Cremer, Bierbeek (BE); and Paul Cos, Oostmalle (BE)
Assigned to UNIVERSITEIT ANTWERPEN, Antwerp (BE); and KATHOLIEKE UNIVERSITEIT LEUVEN, Leuven (BE)
Appl. No. 16/631,878
Filed by Katholieke Universiteit Leuven, Leuven (BE); and Universiteit Antwerpen, Antwerp (BE)
PCT Filed Jul. 5, 2018, PCT No. PCT/EP2018/068192
§ 371(c)(1), (2) Date Jan. 17, 2020,
PCT Pub. No. WO2019/015975, PCT Pub. Date Jan. 24, 2019.
Claims priority of application No. 1711512 (GB), filed on Jul. 18, 2017; and application No. LU100445 (LU), filed on Sep. 20, 2017.
Prior Publication US 2020/0138786 A1, May 7, 2020
Int. Cl. A61K 31/4164 (2006.01); A61P 31/10 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 31/14 (2006.01)
CPC A61K 31/4164 (2013.01) [A61K 9/0034 (2013.01); A61K 9/06 (2013.01); A61K 31/14 (2013.01); A61P 31/10 (2018.01)] 19 Claims
 
1. A pharmaceutical composition comprising a physiologically acceptable carrier and a mixture of miconazole or a salt thereof and domiphen bromide, wherein the mixture is fungicidal against Candida biofilms.