US 12,452,532 B2
Focus quality determination through multi-layer processing
Jiuliu Lu, Miami, FL (US); Bian Qian, Miami, FL (US); John S. Riley, Miami, FL (US); Bart Wanders, Trabuco Canyon, CA (US); and Ken Good, Pasadena, CA (US)
Assigned to Beckman Coulter, Inc., Miami, FL (US)
Filed by Beckman Coulter, Inc., Miami, FL (US)
Filed on Jun. 11, 2024, as Appl. No. 18/740,301.
Application 18/740,301 is a continuation of application No. PCT/US2022/052702, filed on Dec. 13, 2022.
Claims priority of provisional application 63/291,044, filed on Dec. 17, 2021.
Prior Publication US 2024/0357232 A1, Oct. 24, 2024
Int. Cl. H04N 23/67 (2023.01); G01N 15/01 (2024.01); G01N 15/1434 (2024.01); G06T 3/40 (2024.01); G06T 7/00 (2017.01)
CPC H04N 23/67 (2023.01) [G01N 15/01 (2024.01); G01N 15/1436 (2013.01); G06T 3/40 (2013.01); G06T 7/0012 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/10148 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30024 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A system for assessing focal quality of blood cell images comprising:
a) a camera adapted to capture images of blood samples;
b) a non-transitory computer readable medium storing:
i. a plurality of sets of convolution filters;
ii. a fully connected network layer; and
iii. instructions operable to, when executed by a processor:
A) for each set of convolution filters, generate an output having a depth equal to that set of convolution filters' cardinality by performing acts comprising, for each convolution filter in that set of convolution filters, convolving an input with that convolution filter, wherein:
I) the input for a first set of convolution filters is an image captured by the camera; and
II) for each set of convolution filters other than the first set of convolution filters, the input for that set of convolution filters is an output generated by a different set of convolution filters; and
B) generate a focus distance by performing acts comprising, providing an output generated for a set of convolution filters as an input to the fully connected network layer.