US 12,449,366 B2
Surface-enhanced Raman spectroscopic method of detecting an anti-cancer drug in a solution
Nasurullah Mahar, Dhahran (SA); Amir Al-Ahmed, Dhahran (SA); and Abdulaziz Abdulrahman Al-Saadi, Dhahran (SA)
Assigned to KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, Dhahran (SA)
Filed by KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, Dhahran (SA)
Filed on Feb. 3, 2023, as Appl. No. 18/164,163.
Prior Publication US 2024/0272078 A1, Aug. 15, 2024
Int. Cl. G01N 21/65 (2006.01); G01N 33/49 (2006.01)
CPC G01N 21/658 (2013.01) [G01N 33/49 (2013.01)] 20 Claims
 
1. A method of detecting an anti-cancer drug in a solution, comprising:
contacting a substrate with the solution; and
measuring a Raman signal of the anti-cancer drug in the solution,
wherein a layer of a nanomaterial is at least partially coated on an outer surface of the substrate,
wherein the anti-cancer drug interacts with the nanomaterial on the outer surface of the substrate in the solution,
wherein the nanomaterial comprises:
silver nanoparticles; and
a V2CTx MXene,
wherein Tx is at least one selected from the group consisting of —OH, —O, and —F.