US 12,449,335 B2
Piston pump syringe column method and device
Douglas T. Gjerde, Saratoga, CA (US)
Appl. No. 18/267,621
Filed by Douglas T. Gjerde, Saratoga, CA (US)
PCT Filed Dec. 19, 2021, PCT No. PCT/US2021/064255
§ 371(c)(1), (2) Date Jun. 15, 2023,
PCT Pub. No. WO2022/140212, PCT Pub. Date Jun. 30, 2022.
Claims priority of provisional application 63/233,743, filed on Aug. 17, 2021.
Claims priority of provisional application 63/128,844, filed on Dec. 21, 2020.
Prior Publication US 2024/0060861 A1, Feb. 22, 2024
Int. Cl. G01N 1/34 (2006.01); G01N 1/40 (2006.01)
CPC G01N 1/34 (2013.01) [G01N 1/4005 (2013.01); G01N 2001/4016 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A syringe column comprising:
a syringe barrel including a first portion and a second portion;
a solvated media bed including a first end, a second end and media selected from the group consisting of chromatographic media, extraction media, and enzymatic media, and disposed within the second portion of the syringe barrel;
a first frit disposed proximal to the second end of the solvated media bed; and
a pumping piston positioned in the syringe barrel proximal to the second end of the solvated media bed wherein the pumping piston comprises a piston stopper or a compression spring, and the piston stopper or the compression spring is configured to prevent the pumping piston from physically contacting the first end of the solvated media bed.