US 12,448,355 B2
Acetyl-CoA carboxylase modulators
Urszula Slomczynska, Ballwin, MO (US); Matthew W. Dimmic, Wildwood, MO (US); William P. Haakenson, Jr., St. Louis, MO (US); Jennifer L. Bennett, St. Louis, MO (US); Barry J. Shortt, New Melle, MO (US); Christina M. Taylor, Chesterfield, MO (US); and Deryck Jeremy Williams, University City, MO (US)
Assigned to Monsanto Technology LLC, St. Louis, MO (US)
Filed by Monsanto Technology LLC, St. Louis, MO (US)
Filed on Apr. 23, 2021, as Appl. No. 17/238,926.
Application 17/238,926 is a division of application No. 16/239,946, filed on Jan. 4, 2019, granted, now 10,995,070.
Application 16/239,946 is a continuation of application No. 14/896,616, granted, now 10,207,995, issued on Feb. 19, 2019, previously published as PCT/US2014/042267, filed on Jun. 13, 2014.
Claims priority of provisional application 61/834,585, filed on Jun. 13, 2013.
Prior Publication US 2021/0246106 A1, Aug. 12, 2021
Int. Cl. C07D 215/14 (2006.01); A01N 25/00 (2006.01); A01N 35/06 (2006.01); A01N 37/10 (2006.01); A01N 37/22 (2006.01); A01N 41/10 (2006.01); A01N 41/12 (2006.01); A01N 43/16 (2006.01); A01N 43/18 (2006.01); A01N 43/42 (2006.01); A01N 43/54 (2006.01); A01N 43/60 (2006.01); A01N 43/713 (2006.01); A01N 43/76 (2006.01); A01N 43/78 (2006.01); A01N 43/82 (2006.01); A01N 43/84 (2006.01); A01N 57/20 (2006.01); A01N 57/24 (2006.01); A01N 63/00 (2020.01); A01N 63/30 (2020.01); A01N 65/08 (2009.01); A61K 31/04 (2006.01); A61K 31/045 (2006.01); A61K 31/095 (2006.01); A61K 31/335 (2006.01); A61K 31/395 (2006.01); A61K 31/47 (2006.01); C07D 215/18 (2006.01); C07D 215/26 (2006.01); C07D 215/36 (2006.01); C07D 257/04 (2006.01); C07D 409/04 (2006.01)
CPC C07D 215/14 (2013.01) [A01N 25/00 (2013.01); A01N 35/06 (2013.01); A01N 37/10 (2013.01); A01N 37/22 (2013.01); A01N 41/10 (2013.01); A01N 41/12 (2013.01); A01N 43/16 (2013.01); A01N 43/18 (2013.01); A01N 43/42 (2013.01); A01N 43/54 (2013.01); A01N 43/60 (2013.01); A01N 43/713 (2013.01); A01N 43/76 (2013.01); A01N 43/78 (2013.01); A01N 43/82 (2013.01); A01N 43/84 (2013.01); A01N 57/20 (2013.01); A01N 57/24 (2013.01); A01N 63/00 (2013.01); A01N 63/30 (2020.01); A01N 65/08 (2013.01); A61K 31/04 (2013.01); A61K 31/045 (2013.01); A61K 31/095 (2013.01); A61K 31/335 (2013.01); A61K 31/395 (2013.01); A61K 31/47 (2013.01); C07D 215/18 (2013.01); C07D 215/26 (2013.01); C07D 215/36 (2013.01); C07D 257/04 (2013.01); C07D 409/04 (2013.01)] 20 Claims
 
1. A method of controlling fungal pathogens, the method comprising administering to a plant, a seed or soil a composition comprising an effective amount of a compound of Formula III, or a salt thereof,

OG Complex Work Unit Chemistry
wherein
R1 is selected from the group consisting of hydrogen, halogen, alkyl, alkoxy, haloalkyl, and haloalkoxy;
R2 is selected from the group consisting of aryl and heteroaryl, each of which may be optionally independently substituted with one or more substituents selected from the group consisting of halogen, OH, CN, alkyl, alkoxy, haloalkyl, haloalkoxy, alkenyl, C1 to C4 hydroxyalkyl, N(R7R8), and NR9C(O)R10, wherein R9 is selected from the group consisting of hydrogen and alkyl and R10 is alkyl;
R3, R4, R5, and R6 are each independently selected from the group consisting of hydrogen, halogen, OH, alkyl, alkoxy, haloalkyl, haloalkoxy, C1 to C4 hydroxyalkyl, N(R7R8), NR9C(O)R10, and C(O)R11, wherein R9 is selected from the group consisting of hydrogen and alkyl and R10 and R11 are alkyl;
X is selected from the group consisting of CH2, O, S, NH, and N(CH3);
Y is selected from the group consisting of OH, NH2, N(H)OH, N(CH3)OH, and N(R7R8);
Z is selected from the group consisting of alkyl, haloalkyl, and cycloalkyl;
and wherein when R2 is substituted with N(R7R8) or when any one of R3, R4, R5, and R6 is N(R7R8), R7 and R8 are each independently selected from the group consisting of hydrogen and alkyl; and
when Y is N(R7R8), R7 and R8 are each independently selected from the group consisting of hydrogen, alkyl, and hydroxyalkyl.