US 12,448,348 B2
Mixed metal oxide catalysed and cavitation influenced process for hydration of nitrile
Thirumalaiswamy Raja, Maharashtra (IN); Nikitra Nihal Chand Gupta, Maharashtra (IN); Vipul Subhash Patil, Maharashtra (IN); and Amrin Sattarkhan Punekar, Maharashtra (IN)
Assigned to Council of Scientific & Industrial Research, New Delhi (IN)
Appl. No. 17/416,742
Filed by COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH, New Delhi (IN)
PCT Filed Dec. 20, 2019, PCT No. PCT/IN2019/050942
§ 371(c)(1), (2) Date Jun. 21, 2021,
PCT Pub. No. WO2020/129088, PCT Pub. Date Jun. 25, 2020.
Claims priority of application No. 201811048598 (IN), filed on Dec. 21, 2018.
Prior Publication US 2022/0048851 A1, Feb. 17, 2022
Int. Cl. B01J 23/46 (2006.01); B01J 19/00 (2006.01); B01J 23/63 (2006.01); B01J 23/652 (2006.01); B01J 37/00 (2006.01); B01J 37/04 (2006.01); B01J 37/08 (2006.01); C07C 231/06 (2006.01)
CPC C07C 231/065 (2013.01) [B01J 19/008 (2013.01); B01J 23/63 (2013.01); B01J 37/0045 (2013.01); B01J 37/0063 (2013.01); B01J 37/04 (2013.01); B01J 37/082 (2013.01)] 8 Claims
OG exemplary drawing
 
1. A metal oxide-catalyzed process for hydration of nitrile using a catalyst of formula (I), under the influence of ultrasonic cavitation of Frequency 16-28 khz to achieve the maximum conversion and selectivity at lower temperature (35° C.) comprising:
heating a reaction mixture of nitrile, solvent, catalyst of formula (I), with or without cavitation influence, at a temperature range of 30 to 140° C. for a time period in the range of 5 to 10 hours (without cavitation and 1 hr with cavitation), to form a respective amide, wherein said nitrile is selected from aliphatic or aromatic nitrile,
wherein the catalyst of formula (I) is represented as:
AXBYCZ   Formula (I)
wherein:
A is a promoter, wherein said promoter is a lanthanide, wherein said lanthanide is selected from the group consisting of divalent metals, trivalent metals and mixtures of oxides of said metals;
x is the weight % of the promoter in the range of 0.01-99;
B is a support, wherein said support is a transition element or an inner transition element;
y is the weight % of catalyst support in the range of 0.01-99;
C is a co-promoter, wherein said co-promoter is selected from oxides of transition elements having variable oxidation states ranging from 1 to 8 from group number VIII;
z is the weight % of the co-promoter in the range of 0.01-25; and
x+y≥75 weight %.