US 12,447,500 B2
Versatile flow through strategy for selective surface modification
Yannan Zhao, Del Mar, CA (US); Florika Macazo, San Diego, CA (US); Rachel Goodridge, San Diego, CA (US); Emily Welch, San Diego, CA (US); Hassan Bohra, Singapore (SG); Sang Park, San Diego, CA (US); Lisa Savagian, San Diego, CA (US); Borhan Chueh, San Diego, CA (US); Thomas Brubaker, Escondido, CA (US); and Shreshtha Mishra, San Diego, CA (US)
Assigned to Illumina, Inc., San Diego, CA (US)
Filed by Illumina, Inc., San Diego, CA (US)
Filed on Dec. 18, 2023, as Appl. No. 18/543,320.
Claims priority of provisional application 63/476,314, filed on Dec. 20, 2022.
Prior Publication US 2024/0207890 A1, Jun. 27, 2024
Int. Cl. B05D 1/38 (2006.01); B05D 7/22 (2006.01); B05D 7/24 (2006.01)
CPC B05D 1/38 (2013.01) [B05D 7/24 (2013.01); B05D 7/22 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A method for modifying an interstitial surface separating recesses from one another, the method comprising:
flowing a first fluid over the interstitial surface and into the recesses, such that the interstitial surface is substantially coated with the first fluid and the recesses are substantially filled with the first fluid;
while the first fluid remains within the recesses, replacing the first fluid coating the interstitial surface with a second fluid comprising a reagent; and
while the first fluid remains within the recesses and after replacing the first fluid coating the interstitial surface with the second fluid, solidifying the first fluid.