US 12,447,464 B2
Polycationic microfibers and methods of using the same
Jaewoo Lee, Durham, NC (US); Bruce A. Sullenger, Durham, NC (US); and Jennifer G. Jackman, Durham, NC (US)
Assigned to Duke University, Durham, NC (US)
Appl. No. 16/472,735
Filed by Duke University, Durham, NC (US)
PCT Filed Dec. 22, 2017, PCT No. PCT/US2017/068262
§ 371(c)(1), (2) Date Jun. 21, 2019,
PCT Pub. No. WO2018/119422, PCT Pub. Date Jun. 28, 2018.
Claims priority of provisional application 62/451,863, filed on Jan. 30, 2017.
Claims priority of provisional application 62/437,802, filed on Dec. 22, 2016.
Prior Publication US 2021/0129110 A1, May 6, 2021
Int. Cl. B01J 20/26 (2006.01); A01N 1/02 (2006.01); A01N 1/143 (2025.01); A61M 1/34 (2006.01); B01D 39/08 (2006.01); B01D 67/00 (2006.01); B01D 69/02 (2006.01); B01D 69/14 (2006.01); B01D 71/28 (2006.01); B01D 71/40 (2006.01); B01D 71/82 (2006.01); B01J 20/28 (2006.01); B01J 20/30 (2006.01); B01J 20/32 (2006.01); D01F 6/42 (2006.01); D01F 6/56 (2006.01); D06M 15/61 (2006.01)
CPC B01J 20/264 (2013.01) [A01N 1/143 (2025.01); B01D 39/083 (2013.01); B01D 67/00042 (2022.08); B01D 69/02 (2013.01); B01D 69/1411 (2022.08); B01D 71/281 (2022.08); B01D 71/401 (2022.08); B01D 71/82 (2013.01); B01J 20/261 (2013.01); B01J 20/28023 (2013.01); B01J 20/3007 (2013.01); B01J 20/321 (2013.01); B01J 20/3272 (2013.01); B01J 20/3293 (2013.01); D01F 6/42 (2013.01); D01F 6/56 (2013.01); D06M 15/61 (2013.01); A61M 1/34 (2013.01); B01D 2239/0421 (2013.01); B01D 2239/0428 (2013.01); B01D 2325/16 (2013.01); D06M 2400/01 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A polycationic microfiber comprising
a high-aspect-ratio polymeric core, the polymeric core consisting of a blend of a first core polymer and a second core polymer; and
a polycationic polymer immobilized on the surface of the polymeric core;
wherein the weight ratio of the first core polymer to the second core polymer is about 1.5:1 to about 1:1.5; and
wherein the first core polymer consists of poly(styrene-alt-maleic anhydride).