US 12,447,344 B2
Paresthesia-free spinal cord stimulation occurring at lower frequencies and sweet spot searching using paresthesia
Que T. Doan, West Hills, CA (US); Jianwen Gu, Valencia, CA (US); Ismael Huertas Fernandez, Madrid (ES); Rosana Esteller, Santa Clarita, CA (US); and Michael A. Moffitt, Saugus, CA (US)
Assigned to Boston Scientific Neuromodulation Corporation, Valencia, CA (US)
Filed by Boston Scientific Neuromodulation Corporation, Valencia, CA (US)
Filed on Mar. 28, 2025, as Appl. No. 19/094,434.
Application 19/094,434 is a continuation of application No. 18/807,019, filed on Aug. 16, 2024, granted, now 12,285,609.
Application 18/807,019 is a continuation of application No. 18/612,591, filed on Mar. 21, 2024, granted, now 12,268,875.
Application 18/612,591 is a continuation of application No. 17/089,538, filed on Nov. 4, 2020, granted, now 11,944,816, issued on Apr. 2, 2024.
Application 17/089,538 is a continuation of application No. 16/806,065, filed on Mar. 2, 2020, granted, now 11,338,141, issued on May 24, 2022.
Application 16/806,065 is a continuation of application No. 16/100,904, filed on Aug. 10, 2018, granted, now 10,576,282, issued on Mar. 3, 2020.
Claims priority of provisional application 62/693,543, filed on Jul. 3, 2018.
Claims priority of provisional application 62/544,656, filed on Aug. 11, 2017.
Prior Publication US 2025/0222260 A1, Jul. 10, 2025
This patent is subject to a terminal disclaimer.
Int. Cl. A61N 1/36 (2006.01); A61N 1/05 (2006.01); A61N 1/372 (2006.01); A61N 1/06 (2006.01)
CPC A61N 1/36062 (2017.08) [A61N 1/0551 (2013.01); A61N 1/36021 (2013.01); A61N 1/36071 (2013.01); A61N 1/36185 (2013.01); A61N 1/37247 (2013.01); A61N 1/06 (2013.01); A61N 1/36132 (2013.01); A61N 1/37235 (2013.01); A61N 1/37252 (2013.01)] 26 Claims
OG exemplary drawing
 
1. A method of providing therapeutic pain relief without paresthesia to a patient having an implantable spinal cord stimulator comprising an electrode array comprising plurality of electrodes, the method comprising:
providing a test stimulation waveform that results in paresthesia via one or more first electrodes of the plurality of electrodes, wherein the one or more first electrodes are a subset of electrodes comprising less than all electrodes of the plurality of electrodes of the electrode array, wherein the test stimulation waveform comprises first actively-driven biphasic pulses, wherein the first actively-driven biphasic pulses are provided at a frequency of 130 Hz or less and at a first amplitude;
receiving feedback from the patient that the test stimulation waveform at least in part treats or covers the pain with paresthesia; and
providing a therapeutic stimulation waveform that results in therapeutic pain relief without paresthesia within a period of one hour or less via the one or more first electrodes of the plurality of electrodes, wherein the period of one hour or less is relative to an initial time at which the therapeutic stimulation waveform is provided, wherein the test stimulation waveform and the therapeutic stimulation waveform are provided at a same location or region of the electrode array, wherein the therapeutic stimulation waveform comprises second actively-driven biphasic pulses, wherein the second actively-driven biphasic pulses are provided at a frequency of 130 Hz or less and with a second amplitude lower than the first amplitude of the first actively-driven biphasic pulses, wherein the first actively-driven biphasic pulse and the second actively-driven biphasic pulse are charge-balanced,
wherein the first and second actively-driven biphasic pulses are provided at a same frequency.