US 12,447,293 B2
Dry powder inhaler and system for drug delivery
Chad C. Smutney, Watertown, CT (US); P. Spencer Kinsey, Sandy Hook, CT (US); Carl R. Sahi, Coventry, CT (US); Benoit Adamo, North Salem, NY (US); and John M. Polidoro, Tolland, CT (US)
Assigned to MannKind Corporation, Westlake Village, CA (US)
Filed by MannKind Corporation, Westlake Village, CA (US)
Filed on Oct. 27, 2021, as Appl. No. 17/512,529.
Application 17/512,529 is a continuation of application No. 15/954,435, filed on Apr. 16, 2018, granted, now 11,185,645.
Application 15/954,435 is a continuation of application No. 15/098,219, filed on Apr. 13, 2016, granted, now 10,751,488, issued on Aug. 25, 2020.
Application 15/098,219 is a continuation of application No. 13/830,328, filed on Mar. 14, 2013, granted, now 9,339,615, issued on May 17, 2016.
Application 13/830,328 is a continuation of application No. 12/484,137, filed on Jun. 12, 2009, granted, now 8,424,518, issued on Apr. 23, 2013.
Claims priority of provisional application 61/157,506, filed on Mar. 4, 2009.
Claims priority of provisional application 61/061,551, filed on Jun. 13, 2008.
Prior Publication US 2022/0047821 A1, Feb. 17, 2022
Int. Cl. A61M 15/00 (2006.01); A61K 9/00 (2006.01); A61K 38/17 (2006.01); A61K 38/22 (2006.01); A61K 38/26 (2006.01); A61K 38/28 (2006.01); A61K 47/22 (2006.01); A61K 38/00 (2006.01)
CPC A61M 15/0045 (2013.01) [A61K 9/0075 (2013.01); A61K 38/1709 (2013.01); A61K 38/22 (2013.01); A61K 38/26 (2013.01); A61K 38/28 (2013.01); A61K 47/22 (2013.01); A61M 15/0021 (2014.02); A61M 15/0023 (2014.02); A61M 15/0028 (2013.01); A61M 15/0043 (2014.02); A61M 15/0048 (2014.02); A61M 15/0086 (2013.01); A61M 15/0091 (2013.01); A61K 38/00 (2013.01); A61M 2202/064 (2013.01); A61M 2205/6081 (2013.01); A61M 2206/20 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A dry powder inhaler comprising:
a sled or slide tray,
a mouthpiece, and
a cartridge including a container, a lid, and at least one opening configured as an inlet and at least one opening configured as an outlet,
wherein the container and the lid are both rigid parts,
wherein movement of the mouthpiece actuates movement of the container relative to the lid from a powder containment position to a dosing position,
wherein the dry powder inhaler is configured to attain an open or container loading position, and a closed or dosing position,
wherein the mouthpiece actuates the sled or slide tray during movement between the open position and the closed position or from the closed position to the open position,
wherein the container includes a dry powder including a vasoactive agent, and
wherein the dry powder has a rugosity of about 11 to about 16.