| CPC A61M 1/95 (2021.05) [A61F 13/00051 (2013.01); A61F 13/00991 (2013.01); A61F 13/01017 (2024.01); A61F 13/0206 (2013.01); A61M 2205/0238 (2013.01); A61M 2207/00 (2013.01)] | 13 Claims |

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1. A method of manufacturing a wound dressing comprising:
coating a first, wound-facing side of a flexible substrate with a first coating, the substrate comprising a second side opposite the first side, the first side of the substrate supporting a plurality of electronic components and a plurality of electronic connections, wherein the first coating is applied to at least one of one or more electronic components of the plurality of electronic components or one or more electronic connections of the plurality of electronic connections and not to at least some regions of the first side of the substrate that do not include electronic components or electronic connections;
coating the first side of the substrate with a second coating including the at least some regions of the first side of the substrate that do not include electronic components or electronic connections, wherein the second coating is applied over the first coating;
adhering a wound contact layer to the first side and in contact with the second coating, the wound contact layer configured to contact a wound;
then perforating the wound contact layer and the substrate coated with the first and second coating together to create a plurality of through holes through the wound contact layer and the substrate coated with the first and second coating, the plurality of through holes configured to facilitate passage of fluid through the wound contact layer and the substrate;
adhering a protective layer to the wound contact layer, the protective layer configured to be removed to expose the wound contact layer; and
adhering a wicking layer to the second side of the substrate, the wicking layer configured to facilitate passage of fluid.
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