US 12,447,239 B2
3D-printed bioresorbable all-polymer composite soft tissue scaffolds
Banu Akar, Evanston, IL (US); Henry Oliver T. Ware, Evanston, IL (US); Cheng Sun, Wilmette, IL (US); and Guillermo A. Ameer, Chicago, IL (US)
Assigned to Northwestern University, Evanston, IL (US)
Appl. No. 17/310,290
Filed by Northwestern University, Evanston, IL (US)
PCT Filed Jan. 29, 2020, PCT No. PCT/US2020/015561
§ 371(c)(1), (2) Date Jul. 27, 2021,
PCT Pub. No. WO2020/160077, PCT Pub. Date Aug. 6, 2020.
Claims priority of provisional application 62/798,105, filed on Jan. 29, 2019.
Prior Publication US 2022/0133958 A1, May 5, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61L 31/04 (2006.01); A61L 27/26 (2006.01); A61L 27/48 (2006.01); A61L 31/12 (2006.01); A61L 31/18 (2006.01); B29C 64/124 (2017.01); B33Y 10/00 (2015.01); B33Y 70/00 (2020.01); C08F 299/04 (2006.01); C08J 3/24 (2006.01); B33Y 80/00 (2015.01)
CPC A61L 31/041 (2013.01) [A61L 27/26 (2013.01); A61L 27/48 (2013.01); A61L 31/129 (2013.01); A61L 31/18 (2013.01); B29C 64/124 (2017.08); B33Y 10/00 (2014.12); B33Y 70/00 (2014.12); C08F 299/0435 (2013.01); C08F 299/0492 (2013.01); C08J 3/24 (2013.01); B33Y 80/00 (2014.12)] 18 Claims
OG exemplary drawing
 
1. A composition comprising:
(a) an acrylated or methacrylated citric-acid-based polymer;
(b) a photoinitiator compound, wherein exposure to light of an appropriate wavelength results in formation of a first reactive species from the photoinitiator compound;
(c) a thermal initiator compound, wherein exposure to heat results in in formation of a second reactive species from the thermal initiator compound;
(d) a poly(L) lactic acid (PLLA); and
(e) a contrast agent, wherein the contrast agent is radiocontrast agent.