	US 12,447,238 B2
	Antimicrobial tubular conduits
Aniello Cammarano, Ascea (IT); and Luigi Nicolais, Ercolano (IT)
Assigned to SANIDRINK S.R.L., Naples (IT)
Appl. No. 17/907,290
Filed by SANIDRINK S.R.L., Naples (IT)
PCT Filed Mar. 26, 2021, PCT No. PCT/IB2021/052520 § 371(c)(1), (2) Date Sep. 26, 2022, PCT Pub. No. WO2021/191852, PCT Pub. Date Sep. 30, 2021.
Claims priority of application No. 102020000006481 (IT), filed on Mar. 27, 2020.
Prior Publication US 2023/0147595 A1, May 11, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61L 29/16 (2006.01); A47G 21/18 (2006.01); A61L 29/04 (2006.01); A61M 39/08 (2006.01)

CPC A61L 29/16 (2013.01) [A47G 21/188 (2013.01); A61L 29/048 (2013.01); A61M 39/08 (2013.01); A61L 2300/404 (2013.01); A61M 2205/0205 (2013.01)]

12 Claims

1. A tubular conduit comprising an outer surface and an inner surface, wherein at least one portion of the outer surface and/or inner surface is functionalized with at least one antimicrobial peptide consisting of the amino acid sequence having the following general formula:

X₁LX₂WVX₃IWX₄X₅

wherein X₁, X₂, X₃, X₄and X₅are independently selected from the group consisting of K and R and wherein each amino acid is independently in the D or L configuration,

or a salt or solvate thereof.