US 12,447,232 B2
Translucent, dehydrated placental tissue and methods of producing and using the same
John Daniel, Milton, GA (US); Sarah Griffiths, Sandy Springs, GA (US); and Annelise Mowry Roy, Cumming, GA (US)
Assigned to StimLabs LLC, Roswell, GA (US)
Filed by StimLabs LLC, Roswell, GA (US)
Filed on Jul. 12, 2023, as Appl. No. 18/220,928.
Application 17/486,642 is a division of application No. 16/225,733, filed on Dec. 19, 2018, granted, now 11,154,641, issued on Oct. 26, 2021.
Application 18/220,928 is a continuation of application No. 17/486,642, filed on Sep. 27, 2021, granted, now 11,738,115.
Claims priority of provisional application 62/609,771, filed on Dec. 22, 2017.
Prior Publication US 2024/0024536 A1, Jan. 25, 2024
Int. Cl. A61L 27/36 (2006.01); A61K 35/50 (2015.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61P 17/02 (2006.01)
CPC A61L 27/3604 (2013.01) [A61K 35/50 (2013.01); A61L 27/3691 (2013.01); A61L 27/50 (2013.01); A61L 27/54 (2013.01); A61P 17/02 (2018.01); A61L 2430/40 (2013.01)] 23 Claims
 
1. A method of preparing dehydrated umbilical cord or a composition thereof comprising:
a. obtaining an umbilical cord dissected away from the placental disc;
b. dissecting the umbilical cord to completely, substantially, or partially remove the vessel walls of the umbilical cord vein and arteries;
c. performing at least two washing steps to remove blood remnants, wherein at least one of the washing steps comprises washing the umbilical cord in a sodium chloride solution containing a w/v concentration of 18% to 30%, and at least one of the washing steps comprises washing the umbilical cord in purified water;
d. perforating the umbilical cord; and
e. dehydrating the umbilical cord in a dehydration environment;
wherein the umbilical cord and/or the dehydrated umbilical cord comprises Wharton's Jelly.