| CPC A61L 24/0015 (2013.01) [A61K 31/4745 (2013.01); A61K 31/555 (2013.01); A61K 47/6927 (2017.08); A61L 24/0042 (2013.01); A61L 24/06 (2013.01); A61L 26/0014 (2013.01); A61L 26/0061 (2013.01); A61L 26/009 (2013.01); A61L 31/048 (2013.01); A61L 31/148 (2013.01); C08F 220/56 (2013.01); C08F 236/20 (2013.01); A61B 2017/00004 (2013.01); A61B 17/12109 (2013.01); A61B 17/12113 (2013.01); A61B 17/12181 (2013.01); A61L 2300/204 (2013.01); A61L 2300/224 (2013.01); A61L 2400/06 (2013.01); A61L 2430/36 (2013.01)] | 20 Claims |

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1. A method of treatment comprising:
administering a solution including a plurality of particles to a treatment site;
wherein the plurality of particles include a reaction product of at least one monomer, at least one crosslinker, and at least one polymerizable pharmaceutical agent;
wherein the at least one polymerizable pharmaceutical agent is chemically bonded to the particle with a hydrolytically degradable linkage; and
wherein the at least one polymerizable pharmaceutical agent has a structure which is a polymerizable derivative of 7-ethyl-10-hydroxy-camptothecin.
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