US 12,447,018 B2
Heart valve leaflet replacement systems and methods for using them
Thuy Pham, Marietta, GA (US); Caitlin Martin, Marietta, GA (US); and Qian Wang, Marietta, GA (US)
Assigned to SUTRA MEDICAL, INC., Lake Forest, CA (US)
Filed by Sutra Medical, Inc., Marietta, GA (US)
Filed on May 17, 2021, as Appl. No. 17/322,733.
Application 17/322,733 is a continuation of application No. 15/453,518, filed on Mar. 8, 2017, granted, now 11,007,057.
Claims priority of provisional application 62/427,551, filed on Nov. 29, 2016.
Claims priority of provisional application 62/413,693, filed on Oct. 27, 2016.
Claims priority of provisional application 62/305,204, filed on Mar. 8, 2016.
Prior Publication US 2021/0275305 A1, Sep. 9, 2021
Int. Cl. A61F 2/24 (2006.01); A61B 17/04 (2006.01); A61B 17/06 (2006.01)
CPC A61F 2/2445 (2013.01) [A61B 17/0401 (2013.01); A61B 17/0487 (2013.01); A61F 2/2418 (2013.01); A61F 2/243 (2013.01); A61F 2/246 (2013.01); A61F 2/2463 (2013.01); A61B 2017/0409 (2013.01); A61B 2017/0414 (2013.01); A61B 2017/0441 (2013.01); A61B 2017/0464 (2013.01); A61B 2017/06176 (2013.01); A61F 2/2466 (2013.01); A61F 2220/0008 (2013.01); A61F 2230/0013 (2013.01); A61F 2230/0067 (2013.01); A61F 2230/0069 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A prosthetic heart valve for replacing a native leaflet in a diseased heart valve, comprising:
a stent comprising a frame including an upper flared portion configured to span at least a portion of a native annulus of the diseased heart valve in an operative position, and a lower ventricular portion configured to span only a portion of the native annulus and allow for dynamic motion of at least one native leaflet in the operative position;
a plurality of prosthetic leaflets extending inward radially from an inner surface of the frame, wherein the prosthetic leaflets are configured to be moveable from an open to a closed position during a cardiac cycle in the operative position, the prosthetic leaflets attached to the lower ventricular portion at a juncture defined by a three dimensional leaflet-stent attachment curve defining multiple curved attachment points;
a sealing skirt attached to at least one portion of the frame; and
at least one dual-guiding-and-fixation member comprising at least a portion configured to embed in native tissue and at least a portion configured to selectively engage the frame to guide the frame to, and fix the frame relative to the native annulus in the operative position.