US 12,446,874 B2
Cartridge assemblies with absorbable metal staples and absorbable implantable adjuncts
Frederick E. Shelton, IV, Hillsboro, OH (US); Jason L. Harris, Lebanon, OH (US); and Chad E. Eckert, Terrace Park, OH (US)
Assigned to Cilag GmbH International, Zug (CH)
Filed by Cilag GmbH International, Zug (CH)
Filed on Apr. 12, 2022, as Appl. No. 17/718,879.
Claims priority of provisional application 63/186,519, filed on May 10, 2021.
Prior Publication US 2022/0361872 A1, Nov. 17, 2022
Int. Cl. A61B 17/72 (2006.01); A61B 17/064 (2006.01); A61B 17/072 (2006.01); A61B 17/10 (2006.01); A61B 50/30 (2016.01); A61B 90/98 (2016.01); A61L 31/02 (2006.01); A61L 31/04 (2006.01); A61L 31/10 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); A61B 17/00 (2006.01); A61B 17/068 (2006.01); A61B 90/00 (2016.01)
CPC A61B 17/0644 (2013.01) [A61B 17/064 (2013.01); A61B 17/072 (2013.01); A61B 17/07207 (2013.01); A61B 17/105 (2013.01); A61B 50/3001 (2016.02); A61B 90/98 (2016.02); A61L 31/022 (2013.01); A61L 31/028 (2013.01); A61L 31/042 (2013.01); A61L 31/048 (2013.01); A61L 31/10 (2013.01); A61L 31/148 (2013.01); A61L 31/16 (2013.01); A61B 2017/00004 (2013.01); A61B 2017/00022 (2013.01); A61B 2017/00084 (2013.01); A61B 2017/00119 (2013.01); A61B 2017/00845 (2013.01); A61B 17/0686 (2013.01); A61B 2017/0688 (2013.01); A61B 2017/07228 (2013.01); A61B 2017/07235 (2013.01); A61B 2017/07257 (2013.01); A61B 2017/07264 (2013.01); A61B 2017/07271 (2013.01); A61B 2017/07278 (2013.01); A61B 2017/07285 (2013.01); A61B 2050/3004 (2016.02); A61B 2090/0807 (2016.02)] 19 Claims
OG exemplary drawing
 
1. A surgical staple cartridge assembly, comprising:
a cartridge body, comprising:
a deck;
a longitudinal slot defined in the deck; and
staple cavities defined in the deck; and
staples removably stored in the staple cavities, wherein the staples are deployable from the staple cavities into tissue of a patient, and wherein the staples comprise substrates comprised of metal that degrades when exposed to a degradation source in the patient, the staples comprising a first subset defining a first plurality of staples and a second subset defining a second plurality of staples; and
an implantable adjunct releasably secured to the deck and comprising a first portion and a second portion, wherein the staples are configured to hold the implantable adjunct to the tissue, wherein the first portion of the implantable adjunct is configured to delay an initiation of the degradation of regions of the first subset of staples at a first degradation rate, wherein the second portion of the implantable adjunct is configured to delay an initiation of the degradation of regions of the second subset of staples at a second degradation rate, different from the first degradation rate, wherein the first portion and the second portion are configured to chemically modify a local environment surrounding the staples to control the first and second degradation rates of the staples after the initial delay, and wherein the first portion and the second portion comprise at least one of a calcification inhibitor or a chelating agent, and the chemical modification is in response to a release of the at least one of the calcification inhibitor or the chelating agent from the implantable adjunct.