US 12,446,809 B2
Imaging method and imaging system
Fang Yang, Shenzhen (CN); and Lei Zhu, Shenzhen (CN)
Assigned to Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen (CN); and Shenzhen Mindray Scientific Co., Ltd., Shenzhen (CN)
Filed by SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD., Guangdong (CN); and SHENZHEN MINDRAY SCIENTIFIC CO., LTD., Guangdong (CN)
Filed on Apr. 22, 2021, as Appl. No. 17/237,901.
Application 17/237,901 is a continuation of application No. PCT/CN2018/111659, filed on Oct. 24, 2018.
Prior Publication US 2021/0330226 A1, Oct. 28, 2021
Int. Cl. A61B 5/15 (2006.01); A61B 5/00 (2006.01); A61B 8/00 (2006.01); A61B 8/08 (2006.01)
CPC A61B 5/150083 (2013.01) [A61B 5/0095 (2013.01); A61B 8/0891 (2013.01); A61B 8/461 (2013.01)] 14 Claims
OG exemplary drawing
 
1. An imaging method, comprising:
within a first period, emitting a first laser to a target body;
receiving a first photoacoustic signal returned from the target body;
determining a first photoacoustic image of the target body according to the first photoacoustic signal;
within a second period, emitting a second laser to the target body, wherein the second period does not overlap with the first period;
receiving a second photoacoustic signal returned from the target body, wherein a wavelength of the second laser is different from that of the first laser;
determining a second photoacoustic image of the target body according to the second photoacoustic signal;
determining blood oxygen saturation values of all pixel points corresponding to the target body according to the first photoacoustic image and the second photoacoustic image;
generating a blood oxygen image of the target body according to the blood oxygen saturation values of all pixel points corresponding to the target body;
determining positions of each pixel point of a target tissue in the blood oxygen image to determine an area corresponding to the target tissue in the blood oxygen image; and extending a preset range centered on the area corresponding to the target tissue to a peripheral and then removing the area corresponding to the target tissue, so as to obtain a peripheral area of the target tissue in the blood oxygen image;
determining a first blood oxygen saturation value of the area corresponding to the target tissue and a second blood oxygen saturation value of the peripheral area of the target tissue;
determining a blood oxygen ratio of the first blood oxygen saturation value to the second blood oxygen saturation value;
determining a number of pixel points of blood vessels and a number of all pixel points corresponding to the target body, wherein each pixel point of the blood vessels has a blood oxygen saturation value greater than a threshold value; and
determining a blood vessel density according to the number of pixel points of the blood vessels and the number of all pixel points corresponding to the target body; and
analyzing the target tissue according to the blood vessel density and the blood oxygen ratio to obtain an analysis result of the target tissue.