| CPC A61B 5/065 (2013.01) [A61B 1/041 (2013.01); A61B 5/002 (2013.01); A61B 5/0086 (2013.01); A61B 5/073 (2013.01); A61B 5/6861 (2013.01); A61B 5/7264 (2013.01); H04B 10/1143 (2013.01); H04B 13/00 (2013.01); A61B 5/0017 (2013.01); A61B 2560/0443 (2013.01); A61B 2560/0462 (2013.01); A61B 2562/162 (2013.01)] | 20 Claims |

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1. An ingestible device, comprising:
a housing, comprising:
a chamber configured to store a therapeutic agent;
an actuator having a first state in which the therapeutic agent is stored in the chamber and
a second state in which the therapeutic agent is released from the chamber to an exterior of the housing; and
a detector configured in a first configuration to detect a first light characteristic of a GI tract of a subject and in a second configuration to detect a second light characteristic of the GI tract of the subject, the first light characteristic and the second light characteristic in a spectrum selected from the group consisting of a red spectrum, a blue spectrum and a green spectrum; and
a microcontroller configured to determine a location of the ingestible device in a GI tract of a subject based on the first light characteristic of the GI tract and the second light characteristic of a GI tract and based on the location of the ingestible device in the GI tract of the subject detected by the detector, cause the actuator to move from its first state to its second state so that the therapeutic agent is delivered to the exterior of the ingestible device.
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